CLINICAL PERFORMANCE INGREDIENT

KSM-66 ASHWAGANDHA

150mg per Serving. 27.9% Cortisol Reduction at Two Servings Daily. Most Clinically Studied Ashwagandha Extract.

27.9%

Cortisol reduction*

44%

Stress reduction*

24+

Human clinical trials

60 DAYS

Time to results

WHAT IT IS

NOT YOUR AVERAGE ASHWAGANDHA

KSM-66 is not generic ashwagandha. It is a patented, full-spectrum root extract developed by Ixoreal Biomed, concentrated to 5% withanolides using a proprietary water-based extraction that preserves the root's full natural compound profile. No leaf material. No synthetic isolation. No solvent residue. That precision is the reason it has become the most clinically studied ashwagandha root extract in the world.

NutraLife uses KSM-66 at 150mg per serving. At the recommended two servings daily, that reaches 300mg, the dose used in the foundational cortisol reduction research. Same form. Same dose. Disclosed on every can.

THE CLINICAL EVIDENCE

24+ HUMAN TRIALS. CONSISTENT RESULTS.

KSM-66 is one of the most extensively studied branded ingredients in performance nutrition, with research spanning more than 24 published human trials. Across independent studies, the results are consistent: measurable reductions in cortisol and perceived stress, improvements in sleep quality, support for healthy testosterone levels in men, and meaningful gains in muscle strength and recovery markers in training populations.

HOW IT WORKS

CORTISOL. CONTROLLED.

Once absorbed, the active compounds in KSM-66 work directly on the body's central stress regulation system, moderating the release of cortisol, the primary hormone that drives chronic stress, disrupted sleep, and slow recovery. This is an adaptogenic mechanism, not a stimulant. KSM-66 does not mask stress or override it temporarily. It recalibrates the hormonal response that produces it.

At two servings daily, the published research documents a 27.9% reduction in serum cortisol over 60 days. Lower cortisol. Better recovery. Improved sleep quality.

THE RECOVERY PILLAR

3 RECOVERY SYSTEMS. 1 FORMULA.

KSM-66 does not work in isolation. NutraLife pairs KSM-66 with a full Electrolyte Complex and the dual nitric oxide system of Nitrosigine and L-Citrulline, building recovery from three angles in a single formula: hormonal, cellular, and circulatory.

KSM-66 moderates cortisol and supports sleep quality. The Electrolyte Complex restores the minerals training depletes. Nitrosigine and L-Citrulline accelerate blood flow to working muscle. One formula. Three recovery systems.

GOT QUESTIONS?

FREQUENTLY ASKED QUESTIONS

What is KSM-66 ashwagandha and how is it different from regular ashwagandha?

KSM-66 is a patented, full-spectrum ashwagandha root extract produced by Ixoreal Biomed. It is concentrated to 5% withanolides using a proprietary water-based extraction that retains the full natural compound profile of the root, no leaf material, no synthetic isolation, no solvent residue. Generic ashwagandha varies widely in quality, potency, and form, which is why the published research does not transfer cleanly between products. KSM-66 is the most clinically studied ashwagandha extract available, and NutraLife uses it at 150mg per serving so the dose in every can is disclosed and matches the form studied in the published research.

How long does it take for KSM-66 to work?

The published cortisol reduction research on KSM-66 documents measurable results at 60 days of daily use at the 300mg clinical dose. Adaptogens are not stimulants. They work through the hypothalamic-pituitary-adrenal axis to recalibrate the body's stress response over time, not through an immediate sensory hit. NutraLife delivers 150mg of KSM-66 per serving, and at the recommended two servings daily the formula reaches the 300mg threshold the research is built on. Daily use is how this ingredient delivers its full clinical effect.

What does the 27.9% cortisol reduction actually mean?

The 27.9% figure comes from a double-blind, placebo-controlled trial measuring serum cortisol in chronically stressed adults given 300mg of KSM-66 daily for 60 days. Cortisol is the body's primary stress hormone, and chronically elevated cortisol disrupts recovery, sleep quality, and hormonal balance. A 27.9% reduction is a clinically meaningful drop in the physiological signal that drives stress symptoms and recovery debt. NutraLife uses KSM-66 at 150mg per serving so two servings daily reaches the 300mg dose used in the published research.

Why does NutraLife use KSM-66 alongside the other ingredients in the formula?

Recovery is not a single-pathway problem. KSM-66 addresses hormonal recovery by moderating cortisol and supporting sleep quality. The full Electrolyte Complex replenishes cellular hydration lost through training. Nitrosigine at 1,500mg and L-Citrulline at 1,000mg drive blood flow that delivers oxygen and nutrients to recovering muscle. NutraLife pairs KSM-66 with these systems because recovery happens across hormonal, cellular, and circulatory axes simultaneously, and a complete recovery formula has to address all three at once.

Is 150mg the right dose of KSM-66?

NutraLife delivers KSM-66 at 150mg per serving with two servings daily as the recommended use protocol. That reaches 300mg, the exact dose used in the foundational cortisol reduction research on this extract. The study that documents the 27.9% cortisol reduction was conducted at 300mg per day for 60 days. NutraLife matches that protocol so the clinical outcome the research documents holds in practice. The dose is disclosed on every label so you can verify it for yourself.

Can I use NutraLife every day if it contains KSM-66?

Yes. KSM-66 is specifically formulated for sustained daily use, and the published research on this extract is built on daily protocols rather than single-dose effects. It is not a stimulant, it does not build tolerance the way stimulant compounds do, and it does not produce a crash. NutraLife is designed as a daily performance formula, and the recommended two servings daily reaches the 300mg KSM-66 dose used in the cortisol reduction research.

What is the difference between KSM-66 and other ashwagandha extracts?

KSM-66 is a specific full-spectrum root extract patented by Ixoreal Biomed, concentrated to 5% withanolides using a water-based extraction that preserves the natural ratio of bioactive compounds in the ashwagandha root. Other ashwagandha extracts vary in extraction method, withanolide concentration, and plant material used, some include leaf, some include stems, some use solvent extraction that alters the compound profile. Those differences are why clinical results do not transfer cleanly between extracts. NutraLife specifies KSM-66 by name on the label because the form of ashwagandha matters as much as the dose.

Explore the Formula

Every ingredient. Every dose. Fully disclosed.

Nitrosigine

1,500mg | Blood Flow

KSM-66 Ashwagandha

150mg | Recovery

L-Citrulline

1,000mg | Blood Flow

Electrolyte Complex

Full Spectrum | Hydration

Dynamine

60mg | NutraLife Plus Only

Caffeine

150mg | NutraLife Plus Only

References

NutraLife ingredient claims are supported by peer-reviewed published research. The following studies were referenced in the development of this page.

1. Chandrasekhar K, Kapoor J, Anishetty S. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian Journal of Psychological Medicine. 2012;34(3):255-262.

2. Wankhede S, Langade D, Joshi K, Sinha SR, Bhattacharyya S. Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial. Journal of the International Society of Sports Nutrition. 2015;12:43.

3. Lopresti AL, Smith SJ, Malvi H, Kodgule R. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: a randomized, double-blind, placebo-controlled study. Medicine (Baltimore). 2019;98(37):e17186.

4. Salve J, Pate S, Debnath K, Langade D. Adaptogenic and anxiolytic effects of ashwagandha root extract in healthy adults: a double-blind, randomized, placebo-controlled clinical study. Cureus. 2019;11(12):e6466.

*Outcomes measured at two servings daily (300mg). Based on published clinical research at this protocol.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.